Cannabinoids as molecules are too large to permeate beyond the skin, so unless a topically applied cannabis product contains transdermal carriers to break through the stratum corneum (outer layer of skin), topicals are simply skin-deep and local. Transdermal, by definition, is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.
Mary's Patches are typically different than competing varieties. By applying the Transdermal Patches on areas of the body with thin skin and a lot of veins, the cannabis can permeate into the bloodstream for a full body effect similar to smoking or eating edibles. Mary’s patches, which onset in 15-30 minutes and have a duration of between 8 and 12 hours. The effect is an even, slow time-release. Some may feel the patch effects for longer than average, and it’s suggested to leave patches on for approximately 24 hours for the first few uses to gauge effects. We recommend the inside of the wrist, top of the foot or back of the knee for patch placement. Thin skin with a lot of veins is the goal, so that the cannabis oil can transdermally absorb into an advantageous area for systemic. Patches tend to not effect at their full potential if placed on areas not of this nature. For anxiety or a sore back, it’s best to apply the patch on the inner wrist, etc. It’s important that the area of skin under the patch is cleaned prior to application – either with alcohol or soap and water.
Mary's patches are heat, sweat and water resistant so they will stay in place during active use. Because Mary's patches are made with distillate (other than THCa), the cannabis oil is not visible, slick or likely to cause skin irritation.
Patches can be cut down and micro-dosed without activation so that partials can be saved for later use. When cutting down patches, the dosage will proportionately align, but the 8-12 hour time-frame remains. Our packaging is heat/light resistant, thus, a great place to store unused patches.
An intoxicating effect is possible with Mary's transdermal products. The indica and sativa patches will more than likely cause a “high” feeling. The indica and sativa dominances are created with terpene blends. All of Mary’s patches have a unique and consistent terpene blend that’s been created to best synergize with the featured cannabinoid profile. Our terpenes are naturally derived from non-cannabis botanicals.
Time-release technology – slow and steady, when it hits the bloodstream is a function of skin type and where patch is applied on the body. The patch release is activated when applied to something w/o the formulation.
Being better hydrated allows for systemic transdermal products to be more effective!
Approximately 20 mg total cannabinoids per patch. (10 mg CBD - 10 mg THC)
Mary's patches can be cut down, which will proportionately split the dosage while retaining the 8-12 hour time-release. Approximately 30 minute onset.